PHARMACIST GRADE II, EXAM DATE:21-10-2015

1.Physotigmine act as a cholinergic drug by:

A.Directly binding with nicotinic receptors

B.Binding with Muscarinic receptors

C.Inhibiting cholinesterase enzyme

D.Bind with B1 receptors

Ans:C

2.Which among the following is not a natural insecticide?

A.Chrysanthemum cinerariefolium

B.Nicotiana tobacum

C.Ryania speciosa

D.Piper nigrum

Ans:D

3.Most common adverse effect of non steroidal ant-inflammatory agent:

A.CNS toxicity

B. Gastro intestinal toxicity

C.Cardiac toxicity

D.Skin rashes

Ans:B

4.Epinephrine is not used in:

A.Bronchospasm

B.Hypertension

C.Hypersensitivity reaction

D.Increased intra ocular pressure

Ans:B

5.Barbiturate which is used for the induction of anaesthesia is:

A.Phenobarbitone

B.Secobarbital

C.Mephobarbital

D.Thiopentone sodium

Ans:D

6.A highly selective cox-2 inhibitor is:

A.Tenoxicam

B.Ketoprofen

C.Celecoxib

D.Ketorolac

Ans:C

7.An antiviral drug used for the treatment of Parkinsonism is:

A.Amantadine

B.Levodopa

C.Biperiden

D.Selegiline

Ans:A

8.A proton Pump inhibitor commonly used in the treatment of peptic ulcer is:

A.Sucralfate

B.Cimetidine

C.Aluminium hydroxide gel

D.Omeprazole

Ans:D

9.Which among the following drugs is used as an emetic?

A.Apomorphine

B.Codeine

C.Papaverine

D.Noscopine

Ans:A

10.Antibiotic which is used as a cytotoxic agent is:

A.Piperacillin

B.Ampicillin

C.Cloxacillin

D.Actinomycin D

Ans:D

11.Colchicum autumnale belongs to the family:

A.Liliaceae

B.Rutaceae

C.Moringaceae

D.Rhamnaceae

Ans:A

12.The act which controls the advertisement of certain drugs:

A.The drug and Magic remedies Act 1955

B.Insecticides Act 1948

C.The Pharmacy Act 1948

D.Poisons Act 1919

Ans:A

13.Kwashiorkor is a disease associated with the deficiency of:

A.Vitamin B₁₂

B.Vitamin D

C.Carbohydrate

D.Protein

Ans:D

14.Type of emulsion may be determined by:

A.Leakage test

B.Conductivity test

C.Toxicity test

D.Bubble point test

Ans:B

15.Drugs colored coated powdered or polished to conceal damage or to appear to be of better therapeutic value than they really are is called:

A.Spurious drug

B.Misbranded  drug

C.Adulterated drug

D.Reprocessed drug

Ans:B

16.Grease spot test is used to identify:

A.Protein

B.Carbohydrate

C.Lipid

D.Alkaloid

Ans:C

17.Vitamin A is also called:

A.Anti Scurvitic Vitamin

B.Antisterilitic Vitamin

C.Antihaemorrhagic Vitamin

D.Antixerophthalic Vitamin

Ans:D

18.The foreign bodies which are present in our body are collectively called as:

A.Xenobiotics

B.Probiotics

C.Antibiotics

D.Heptane

Ans:A

19.Primrose leaves is an adulterant of:

A.Datura

B.Digitalis

C.Senna

D.Belladona

Ans:B

20.Anthraquinone glycosides are present in:

A.Ispaghula

B.Ephidrine

C.Aswagandha

D.Rhubarb

Ans:D

21.Physically distinct forms of same enzyme are called:

A.Isoenzyme

B.Co-enzyme

C.Apoenzyme

D.Holoenzyme

Ans:A

22.Albinism is produced due to the defect in biosynthesis of:

A.Tyrosine

B.Melanin

C.Valine

D.Isoleucine

Ans:B

23.Diseases and ailments which drug may not purport to prevent or cure is included in:

A.Schedule C1

B.Schedule G

C.Schedule J

D.Schedule M

Ans:C

24.Which one among the following is classified as a diuretic drug?

A.Punarnava

B.Ipecacunha

C.Cinchona

D.Liquorice

Ans:A

25.Total energy gained from one mol of glucose under aerobic condition is:

A.8 ATP

B.38 ATP

C.12 ATP

D.36 ATP

Ans:D

26.Holding temperature for moist heat sterilization is 115-118⁰C for:

A.30 minutes

B.15 minutes

C.0 minutes

D.5 minutes

Ans:B

27.Chemical test for opium is done to check the presence of

A.Ferulic acid

B.Eugenol

C.Meconic acid

D.Tartaric acid

Ans:C

28.The immunity in which the body receives readymade antibody is called:

A.Active immunity

B.Passive immunity

C.Natural immunity

D.Innate immunity

Ans:B

29.Water which is free from volatile and non-volatile impurities,micro organisms and pyrogens is called:

A.Purified water

B.Potable water

C.Water for injection

D.Sterile water for injection

Ans:C

30.The process in which a solid gets directly converted into vapour is called:

A.Desiccation

B.Sublimation

C.Evaporation

D.Condensation

Ans:B

31.Adult dose of a drug is 240 mg calculated dose for a child of age of 12 years is:

A.60 mg

B.80 mg

C.100 mg

D.120 mg

Ans:D

32.When certain drugs administered repeatedly at short intervals decreased response is obtained is called:

A.Idiosyncrasy

B.Tolerance

C.Tachyphylaxis

D.Antagonism

Ans:C

33.Liquid or semi solid preparations applied with friction is called:

A.Lotion

B.Ointment

C.Jelly

D.Liniment

Ans:D

34.1:500 concentration of a drug means:

A.1 mg in 500 ml

B.1 kg in 500 kg

C.1 g in 500 ml

D.1 g in 500 L

Ans:C

35.Person who wishes to manufacture of preparations containing alcohol or other narcotic substance is required to obtain license from:

A.Drugs inspector

B.Excise Commissioner

C.Drugs Controller

D.Director of Health Services

Ans:B

36.The proportion of oil:water:gum in arachis oil emulsion is:

A.4:2:1

B.3:2:1

C.2:2:1

D.2:1:1

Ans:A

37.g.o.d.means:

A.Four times a day

B.Every other day

C.As needed

D.After meals

Ans:B

38.Superior and inferior vanacava enter:

A.Right atrium

B.Left atrium

C.Right ventricle

D.Left ventricle

Ans:A

39.Rheumatoid arthritis is caused by:

A.Mycobacterium tuberculosis

B.Deficiency of calcium

C.Uric and crystals

D.Autommune disorder

Ans:D

40.Vasopressin is secreted by:

A.Hypothalamus

B.Anterior pituitary

C.Posterior pituitary

D.Adrenal medulla

Ans:C

41.Diabetis mellitus is caused when there is:

A.A deficiency of insulin

B.A deficiency of glucogon

C.A decreased response of kidneys of vasopressin

D.A deficiency of growth hormone

Ans:A

42.Any substance capable of triggering an immune response is called a:

A.Heptane

B.Antibody

C.Interferon

D.Antigen

Ans:B

43.HIV virus destroys:

A.T helper cells

B.Eosinophils

C.Basophils

D.Monocytes

Ans:A

44.Microcytic hypo chromic anemia is caused by the deficiency of:

A.Vitamin B₁₂

B.Riboflavin

C.Iron

D.Folic acid

Ans:C

45.Otic route is used to deliver drug in to:

A.Eye

B.Ear canal

C.Nose

D.Skin

Ans:B

46.Normal value of creatine clearance:

A.75-125 mL/minute

B.125-175 mL/minute

C.175-250 mL/minute

D.259-275 mL/minute

Ans:A

47.Warfarin interacts with Phynytoin by interfering with:

A.Absorption

B.Protein binding

C.Metabolism

D.Elimination

Ans:B

48.Antidote for iron poisoning is:

A.Deferoxamine

B.Acetyl cystine

C.Dimercaprol

D.Penicillamine

Ans:A

49.Test for water holding capacity is prescribed for

A.Cat gut

B.Absorbent cotton

C.Surgical gauze

D.Sanitary Napkins

Ans:B

50.List of drugs to be purchased in a hospital is prepared by:

A.Chief Pharmacist

B.Hospital superintendent

C.Pharmacy and therapeutic committee

D.Drug technical advisory board

Ans:C

51.Safest and the most efficient method of drug distribution system is:

A.Floor stock system

B.Complete floor stock system

C.Charge floor stock system

D.Unit dose drug distribution system

Ans:D

52.Faithful adherence of the instructions given by Physician/pharmacist is called:

A.Non compliance

B.Pharmaceutical care

C.Patient counseling

D.Patient compliance

Ans:D

53.Articles published in journals are called:

A.Primary literature

B.Secondary literature

C.Teritary source

D.Abstracting

Ans:A

54.Rate of bioavailability is greatest for:

A.Capsule

B.Tablet

C.Suspensions

D.Solution

Ans:D

55.The Vitamin which is given in severe cases of alcoholism is:

A.Ascorbic acid

B.Riboflavin

C.Thiamne

D.Pyridoxine

Ans:C

56.Hemp is pericyclic fibers obtained from the stem of:

A.Linum usitatissimum

B.Corchorous olitorius

C.Cannabis sativa

D.Gossypium herbaceum

Ans:C

57.Basic ring present in pethidine is:

A.Pyrrole

B.Pyridine

C.Thiophene

D.Quinoline

Ans:B

58.Example for a protein which is used in therapy is:

A.Adrenaline

B.Hydrocortisone

C.Insulin

D.Thyroxin

Ans:C

59.Ciprofloxacin belongs to the category of:

A.Fluroguinolones

B.Aminoglycosides

C.Macrolides

D.Cephalosporines

Ans:A

60.Hetro atoms present in chlorpromazine are:

A.Nitrogen and Oxygen

B.Sulphur and Oxygen

C.Nitrogen Sulphur and Oxygen

D.Nitrogen and Sulphur

Ans:D

61.Major side effect of sodium bicarbonate when used as antacid is:

A.Systemic alkalosis

B.Systemic acidosis

C.Metabolic alkalosis

D.Metabolic alkalosis

Ans:A

62.An example for antioxidant is:

A.Sodium bisulphite

B.Sodium lauryl sulphate

C.Sodium potassium tartrate

D.Sodium fluoride

Ans:A

63.Radiopharmaceuticals should be stored in:

A.Aluminium containers

B.Iron containers

C.Borosilicate glass containers

D.Lead containers

Ans:D

64.Citric acid is added in the limit test for iron to:

A.Provide an acidic medium

B.To react  with iron to produce a purple colour

C.To form a complex with iron to prevent precipitation

D.To react with acid radicals to prevent precipitation

Ans:C

65.Inorganic compound which is used as a dentine desensitizer is:

A.Calcium carbonate

B.Strontium chloride

C.Calcium chloride

D.Calcium hypochlorite

Ans:B

66.Gelatin is chemically:

A.A complex carbohydrate

B.Purified wax

C.Hydrous wool fat

D.Hydrolyzeed collagenous material

Ans:D

67.Concentration of alcohol most effective as bacteriacidal is:

A.99%

B.50%

C.70%

D.10%

Ans:C

68.Main drug used for the treatment of syphilis is:

A.Penicillin G

B.Ampicillin

C.Gentamicin

D.Amikacin

Ans:A

69.Which is the second line drug for Tuberculosis?

A.Isoniazid

B.Ciprofoxacin

C.Rifampici

D.Ethambutol

Ans:B

70.Saline cathartics act by:

A.Stimulating the gastro intestinal mucosa

B.Increasing the gastro intestinal motility

C.Increasing the osmotic load of the intestinal tract

D.Decreasing the gastro intestinal motility

Ans:C

71.Dr.Herman Gundert who prepared the first Dictionary in Malayalam is associated with which of the following Missions?

A.Basel Mission

B.Missionaries of Charity

C.English Charitable mission

D.Evangelical Mission

Ans:A

72.In which year did Sree Narayana Guru consecrate the Idol of Siva in Aruvippuram Temple?

A.1912

B.1913

C.1888

D.1903

Ans:C

73.Which of the following is not a part of the preamble to the Indian Constitution?

A.Socialism

B.Secularism

C.Federalism

D.Republic

Ans:C

74.Who among the following wrote the work’Athmanuthapam’?

A.Vagbhadananda

B.Saint Elias Kuriakose Chaavara

C.Sree Narayana Guru

D.Chattambi Swamikal

Ans:B

75.In which year was the Cochin State Prajamandal formed?

A.6 January 1936

B.16 January 1941

C.12 August 1945

D.8 July 1946

Ans:B

76.The power of supreme  Court of India to decide the dispute between the Centre and States falls under  it’s --------------Jurisdiction.

A.Advisory

B.Appellate

C.Writ

D.Original

Ans:D

77.Who suggested the name ‘Abstention Movement’for the same?

A.I.C.Chacko

B.C.Kesavan

C.T.M.Varghese

D.N.V.Joseph

Ans:A

78.Who among the following translated Tagor’s ‘Gitanjali’ for the first time into Malayalam?

A.Kumaranasan

B.G.Sankara Kurup

C.Vallathol

D.S.K.Pottakkad

Ans:B

79.Pick out from the following the prominent woman leader from Malabar who participated in the Freedom Struggle?

A.Akkamma Cherian

B.Anna Chandi

C.A.V.Kuttimalu Amma

D.Thottakkad Madhavi Amma

Ans:C

80.The novelist to have won the ‘Jnanpith Award’ for the first time from Kerala is------------

A.G.Sankara Kurup

B.Thakazhi

C.S.K.Pottakad

D.M.T.Vasudevan Nair

Ans:C

81.The members of the State Public Service Commission are appointed by:

A.Chief Minister

B.Chief Justice

C.Chief Secretary

D.Governor

Ans:D

82.Who among the following was the Chairman of the Guruvayoor Satyagraha Committee?

A.K.Kelappan

B.A.K.Gopalan

C.C.Krishnan

D.Mannathu Padmanabhan

Ans:D

83.Who was the first Vice-Chancellor of Kerala University?

A.Sardar K.M.Panicker

B.Joseph Mundasseri

C.John Mathai

D.M.V.Paili

Ans:C

84.Where is the BRICS Bank being established?

A.China

B.India

C.Brazil

D.South Africa

Ans:A

85.On which date was the National Food Security Act signed into Law?

A.13 September 2013

B12 September 2013

C.26 August 2013

D.3 August 2013

Ans:D

86.Who among the following is the present Chairman of the National Women’s Commission?

A.Mano Sharma

B.Sujatha Singh

C.Lalitha Kumaramangalam

D.Jayanthy Patnaik

Ans:C

87.Who was the founder of ‘Samatwa Samajam’?

A.Ayyankali

B.Chattambi Swamikal

C.Swami Agamananda

D.Ayya Vaikundar

Ans:D

88.Who among the following Keralities,was the Editor of Newspaper,’The Madras Standard’?

A.G.P.Pillai

B.K.P.Kesava Menon

C.Kumaranasan

D.C.V.Kunjuraman

Ans:A

89.Which Article of the Indian Constitution is related to Presidential Rule in States?

A.Article 352

B.Article 356

C.Article 359

D.Article 360

Ans:B

90.Who is popularly known as the ‘Lincoln of Kerala ‘?

A.K.Kelappan

B.Velukutty Arayan

C.A.K.Gopalan

D.Pandit K.P.Karuppan

Ans:D

91.The carthartic property of castor oil is due to the presence of:

A.Linoleic acid

B.Arachidonic acid

C.Ricinoleic acid

D.Stearic acid

Ans:C

92.d-Tubocurarine is a:

A.Neeuromuscular blocking agent

B.Anticholine  esterase

C.Anaesthetic

D.Neuro degenerative agent

Ans:A

93.The schedule which provide standard for ophthalmic preparation:

A.Schedule P

B.Schedule R

C.Schedule FF

D.Schedule Y

Ans:C

94.Citric acid cycle takes place in:

A.Liver

B.Mitochondria

C.Endoplasmic reticulum

D.Nucleic acid

Ans:B

95.The pyrimidine component of RNA is:

A.Adenine

B.Guanine

C.Thymine

D.Uracil

Ans:D

96.Major side effect of chloramphenicol is:

A.Bone marrow depression

B.GIT disturbances

C.Isomnia

D.Profound dyspnea

Ans;A

97.Example for a five membered hetrocyclic compound with one hetro atom is:

A.Pyrimidine

B.Furane

C.Aziridine

D.Phenanthrene

Ans:B

98.One table spoon full is:

A.4 mL

B.6 mL

C.8 mL

D.15 mL

Ans:D

99.Bence Jones Proteins found in urine occur in:

A.Liver diseases

B.Diabetes mellitus

C.Multiple myeloma

D.Thalassemia

Ans:C

100.Preparations of digitals is used in the treatment of:

A.Hypertension

B.Gout

C.Myocardial infraction

D.Congestive cardiac failure

Ans:D