01. Pharmacokinetics is:
a) The study of biological and therapeutic effects of drugs
b) The study of absorption, distribution, metabolism and excretion of drugs
c) The study of mechanisms of drug action
d) The study of method PART I PHARMACOKINETICS s of new drug development
02. What does “pharmacokinetics” include?
a) Complications of drug therapy
b) Drug biotransformation in the organism
c) Influence of drugs on metabolism processes
d) Influence of drugs on genes
03. What does “pharmacokinetics” include?
a) Pharmacological effects of drugs
b) Unwanted effects of drugs
c) Chemical structure of a medicinal agent
d) Distribution of drugs in the organism
04. What does “pharmacokinetics” include?
a) Localization of drug action
b) Mechanisms of drug action
c) Excretion of substances
d) Interaction of substances
05. The main mechanism of most drugs absorption in GI tract is:
a) Active transport (carrier-mediated diffusion)
b) Filtration (aqueous diffusion)
c) Endocytosis and exocytosis
d) Passive diffusion (lipid diffusion)
06. What kind of substances can’t permeate membranes by passive diffusion?
a) Lipid-soluble
b) Non-ionized substances
c) Hydrophobic substances
d) Hydrophilic substances
07. A hydrophilic medicinal agent has the following property:
a) Low ability to penetrate through the cell membrane lipids
b) Penetrate through membranes by means of endocytosis
c) Easy permeation through the blood-brain barrier
d) High reabsorption in renal tubules
08. What is implied by «active transport»?
a) Transport of drugs trough a membrane by means of diffusion
b) Transport without energy consumption
c) Engulf of drug by a cell membrane with a new vesicle formation
d) Transport against concentration gradient
09. What does the term “bioavailability” mean?
a) Plasma protein binding degree of substance
b) Permeability through the brain-blood barrier
c) Fraction of an uncharged drug reaching the systemic circulation following any route administration
d) Amount of a substance in urine relative to the initial doze
10. The reasons determing bioavailability are:
a) Rheological parameters of blood
b) Amount of a substance obtained orally and quantity of intakes
c) Extent of absorption and hepatic first-pass effect
d) Glomerular filtration rate
4 comments:
Hi, there. I am Tom Neil and I wish to describe how life had been for my younger brother living with schizophrenia and how he had been permanently able to overcome this debilitating disease via a naturopathic, herbal method.
Maicon - my kid brother was twenty years old when he was brought to the emergency room by the campus police of the college from which he had been suspended several months ago. A professor had called and reported that he had walked into his classroom, accused him of taking his tuition money, and refused to leave.
Although he had much academic success as a teenager, his behavior had become increasingly odd during the past year. He quit seeing his friends and no longer seemed to care about his appearance or social pursuits. He began wearing the same clothes each day and seldom bathed. He lived with several family members but rarely spoke to any of them. When he did talk to them, he said he had found clues that his college was just a front for an organized crime operation. He had been suspended from college because of missing many classes. My sister said that she had often seen him mumbling quietly to himself and at times he seemed to be talking to people who were not there. He would emerge from my room and ask my family to be quiet even when they were not making any noise.
My father and sister told the staff that Maicon's great-grandmother had had a serious illness and had lived for 30 years in a state hospital, which they believed was a mental hospital. Our mother left the family when Maicon was very young. She has been out of touch with us, and they thought she might have been treated for mental health problems.
Maicon agreed to sign himself into the psychiatric unit for treatment. The whole family except I had agreed to have Maicon transferred to a mental asylum. I knew inwardly there was still some plausible means by which my kid brother could overcome this condition. I knew botanical means of treatment will be more favorable than any other type of treatment, and as such, I had taken a keen interest in the research of naturopathic alternative measures suitable for the treatment of schizophrenia. I had pleaded for some little patience from the family in the delay of the transfer, I was looking forward to proving a point to the entire family, of a positive botanical remedy for this condition.
It was during my ceaseless search on the internet I had been fortunate enough to come across Dr. Utu Herbal Cure: an African herbalist and witch doctor whose professional works had majored on the eradication of certain viral conditions, especially schizophrenia, ( improving the memory capacity positively), via a traditional, naturopathic process and distinguished diet plan. It was by the administration of this herbal specialist that my brother had been able to improve his condition for better.
Before the naturopathic remedy - Maicon's story had reflected a common case, in which a high-functioning young adult goes through a major decline in day-to-day skills. Although family and friends may feel this is a loss of the person they knew, the illness can be treated and a good outcome is possible.
My brother Maicon is just like many other patients out there suffering from this disease. Although he was able to overcome this condition via a naturopathic herbal remedy administered by this African herbal physician and saved completely thus, rekindling the lost joy which had been experienced by the family members.
I wish to use this opportunity to reach across to anyone who may happen to be diagnosed with this disastrous condition to spread the hope of an everlasting herbal remedy that is capable of imposing a permanent end to this disease.
For more information concerning this naturopathic herbal remedy, feel free to contact this African herbal practitioner via email:
drutuherbalcure@gmail.com
My name is Olisa Blessing, I am so happy. I never believe I will be this happy again in life. I have worked as an air hostess ( cabin crew ) for 3years but early last year, I lost my job because of this deadly disease called Herpes virus (HSV).
I never felt sick or noticed any symptoms. Not until the day all workers were asked to bring their current doctor's report card, that was how I got tested and found out that I was Herpes Virus positive and that made me lose my job because it was considered as an STD and is an incurable disease.
I was so depressed to the extent that I started thinking of suicide. I explained my situation to an older friend of mine, who often said to me 'a problem shared is a problem half solved.
She felt solicitude for me, she referred Dr. Utu Herbal Cure to me, that was how I contacted Dr. Utu and got the herbal cure from him that permanently cured me of herpes virus and depression.
I went back to my work a month later with a HERPES NEGATIVE test result from another lab. They were astonished and curious when they saw my HSV NEGATIVE result. They carried out another test on me through their private doctor and they found out I am indeed a HERPES VIRUS FREE PERSON and my position was given back to me.
Beware of impersonators,
Dr. Utu can only be reached at:
drutuherbalcure@gmail.com
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